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Taking a fish oil supplement alone or combined with evening primrose oil reduces joint discomfort in persons suffering from rheumatoid arthritis. This is recommended by a little human study that Serbian researchers at the University of Kragujevac published in Nutrients.

The researchers divided 60 females with rheumatoid arthritis into 3 groups. All females had been on low doses of methotrexate and corticosteroid hormones. When important the females took painkillers.

The participants in the initial group took five fish-oil capsules a day for 12 weeks. Every capsule contained 1 g fish oil, 300 mg DHA and 200 mg EPA. The researchers applied the supplement Omega-three Cardio, manufactured by Organic Wealth. [naturalwealth.rs]

The participants in the second group took two capsules of the exact same supplement just about every day, plus capsules containing evening primrose oil. Every capsule contained 1300 mg evening primrose oil, 949 mg linoleic acid and 117 mg gamma linoleic acid. That supplement was also manufactured by Organic Wealth.

The third group got no supplements – not even placebos.

The study was funded by the Serbian government, not by the supplements business.

The participants who took supplements had substantially significantly less difficulty with sensitive joints. Click on the figures under for a bigger version.

At the finish of the 12 weeks all groups reported that their joints had been significantly less swollen. The reduction was a tiny stronger in the supplementation groups than in the manage group.

The supplementation lowered the quantity of discomfort the participants had and lowered the activity of the arthritis.

“The intake of fishoil alone or combined with evening primrose oil […] induced a important improvement in the clinical status of sufferers with rheumatoid arthritis,” summarised the researchers. “Further investigation with a big quantity of sufferers more than a longer duration is required to confirm the extended-term efficacy of these supplementations.”

Clinical Positive aspects of n-three PUFA and ɤ-Linolenic Acid in Sufferers with Rheumatoid Arthritis


Marine n-three polyunsaturated fatty acids (PUFA) and ɤ-linolenic acid (GLA) are effectively-recognized anti-inflammatory agents that might support in the therapy of inflammatory issues. Their effects had been examined in sufferers with rheumatoid arthritis (two) Procedures: Sixty sufferers with active rheumatoid arthritis had been involved in a potential, randomized trial of a 12 week supplementation with fish oil (group I), fish oil with primrose evening oil (group II), or with no supplementation (group III). Clinical and laboratory evaluations had been completed at the starting and at the finish of the study (three)

The Illness Activity Score 28 (DAS 28 score), quantity of tender joints and visual analogue scale (VAS) score decreased notably following supplementation in groups I and II (p http://www.mdpi.com/2072-6643/9/four/325/htm